Charmost® Derm Line is designed for mid-dermal injection and facial contouring applications.

Indications & Treatment Protocol
Derm Line is a 24 mg/ml BDDE cross-linked hyaluronic acid (HA) filler formulated for the mid-dermis. It is indicated for moderate facial wrinkles, nasolabial folds, marionette lines, and lip enhancement, making it one of the most versatile options in the Charmost® filler range.
| Protocol Parameter | Value |
|---|---|
| HA concentration | 24 mg/ml, BDDE cross-linked |
| Injection depth | Mid-dermis |
| Recommended needle | 27G × 2 |
| Particle size | 0.15 – 0.28 mm |
| Expected duration | 6 – 12 months |
| Touch-up interval | 6 – 12 months, per physician assessment |
A treatment session typically takes 20–30 minutes. Results are visible immediately and settle within 1–2 weeks. Standard aftercare applies: avoid pressing the treated area for 24 hours, skip strenuous exercise, alcohol, and heat exposure (sauna, hot shower) for 24–48 hours, and protect the skin from sun during the first week.
Mechanism of Action
Hyaluronic acid is a water-binding glycosaminoglycan that occurs naturally in human skin. In Charmost® Derm Line, HA is cross-linked with BDDE, which resists enzymatic breakdown and keeps the gel in the mid-dermis for months rather than days.
The medium particle size (0.15–0.28 mm) provides a balance between smoothness and projection: it is cohesive enough to lift and support moderate folds, yet soft enough for dynamic areas such as the lips. Beyond the immediate volumetric correction, HA fillers are reported to stimulate fibroblasts and encourage natural collagen remodeling, supporting longer-term skin quality.
Being HA-based, Derm Line can be dissolved with hyaluronidase if correction is required, offering a reversible safety profile for both patient and clinician.
How Derm Line Compares
| Product | Concentration | Particle size | Injection depth | Needle | Duration |
|---|---|---|---|---|---|
| Fine Line | 24 mg/ml | 0.10 – 0.15 mm | Superficial | 27G | 6 – 12 months |
| Derm Line | 24 mg/ml | 0.15 – 0.28 mm | Mid-dermis | 27G | 6 – 12 months |
| Deep Line | 24 mg/ml | 0.28 – 0.50 mm | Deep dermis | 26G | 8 – 12 months |
Derm Line is the mid-range workhorse of the Charmost® filler family. Choose Derm Line for nasolabial folds, marionette lines, and lip work; move to Fine Line for very delicate areas, or to Deep Line when deeper folds and stronger projection are required.
Treatment Areas
- Lip enhancement
- Nasolabial folds
- Marionette lines
- Facial contouring
FAQ
1. How long does the effect of Derm Line last?
Results typically last 6–12 months for most patients. The exact duration depends on the treated area, injection volume, and individual metabolism.
2. Is Derm Line suitable for lip enhancement?
Yes. Derm Line is a common choice for lip volume and contour because its medium particle size provides natural softness while maintaining shape in a highly mobile area.
3. How is Derm Line different from Deep Line?
Derm Line is injected into the mid-dermis and suits moderate folds and lips. Deep Line uses larger particles (0.28–0.50 mm), is injected into the deep dermis, and is designed for deeper nasolabial folds, cheek augmentation, and chin enhancement.
4. Does Derm Line require anesthesia?
Topical anesthesia is commonly applied before injection, and many formulations also contain lidocaine. The practitioner will decide based on the treatment area and patient tolerance.





